Preheat oven to 350 degrees. Spray a 9" x 5" x 3" loaf pan with non-stick cooking spray. Set aside.
In a small bowl mix together pumpkin, white granulated sugar, and pumpkin pie spice blend. Set aside.
On a clean work surface or cutting board, remove biscuits from can. Split each biscuit in half for 2 layers. After splitting each biscuit in half you should have 16 rounds total laid out on work surface.
Brush melted butter on the tops of the 16 biscuits rounds. Spread 2 tsp of pumpkin mixture onto each butter covered round fully. Sprinkle brown sugar over the pumpkin mixture covered rounds.
Stack 4 rounds together into 4 stacks.
Place each stack into prepared loaf pan on their side. You should visually see 16 dough rounds.
Bake in preheated oven for 40-45 minutes until golden brown and dough is cooked through. You may need to cover with foil about 1/2 way through to keep dough from being too brown. Remove from oven and allow to cool in pan for 10 minutes.
In a medium bowl cream the cream cheese using an electric hand mixer or just a spatula. Add in milk and vanilla and cream again. Sift in powdered sugar 1/4 cup at a time. Add additional milk if needed to get the desired creamy texture.
Invert the pumpkin loaf onto a serving plate and pour icing over the loaf. Sprinkle with crushed pecans. Enjoy.